Research projects

Synthesis of imidazole-based chiral heterocycle skeletons and their use in the synthesis of imidazole-containing cyclopeptides and designing sequential reactions and their capability in supramolecular chemistry 1397.
Synthesis of heterocyclic functional skeletons and their binding to peptide drugs and preparation of active pharmaceutical precursors for peptide radiopharmaceuticals 1396.
Synthesis, lipophilicity and antibacterial properties of indole-like peptides 1395.
Designing multi-component reactions based on chromium and coumarin skeletons and study of their biological and optical properties 1394.
Designing and synthesis of novel peptides and cyclopeptides containing tri-azole ring and evaluation of their anti-cancer properties on several cell lines in 1392.
Synthesis and evaluation of anticancer properties of modern peptide and cyclopeptide samples 1392.
Synthesis of novel hydrazides and their use in the design of multicomponent reactions 1392.
Synthesis, lipophilicity and antibacterial properties of indole-like peptides 1392.
Space-selective synthesis of 3- (anilinoaryl methylene) derivatives -2-oxindoles (modern hesperadine analogues) and evaluation of their anti-cancer properties 1389.
Synthesis, self-decoration, biological properties and solid-state structure of new 2-amino pyrimidine derivatives 1387.
Synthesis of new enkephalin analogues and study of their biological properties 1385.

Presenting technical knowledge for the production of fertirelin acetate peptide, raw material used in animal fertility control.

Synthesis of new peptide derivatives containing RGD-based and disulfide bridge and study of anti-cancer properties 1394.
Designing and synthesis of new analogues of Deferasirox (reducing excess iron) and evaluation of their biological effect 1396.
Synthesis of oxoisoyndolin derivatives and functionalized derivatives of keto-pyrazine 1397.
Designing and synthesis of new derivatives of 2-pyridone, chroman-2-pyridone and 1-amino isoquinoline 1399.

Harnessing the power of post-condensational modification of the GBB reaction products for the construction of new biologically relevant molecular scaffolds, INSF-RFBR Joint Research Project, (2020), Prof. Mikhail Krasavin, Department of Chemistry, St. Petersburg State University, Russia.
Synthesis of supramolecular ligands containing peptide moieties and their application in asymmetric catalysis, Linkage Research Group Program supported by Alexander von Humboldt Foundation, (2017-2020), Prof. Bernhard Breit, Institute of Organic Chemistry, University of Freiburg, Germany.
Imidazole platforms with multiple recognition units, DFG (German Research Foundation), (2019), Prof. Dr. Gebhard Haberhauer, University of Duisburg-Essen, Germany.

Peptide Chemistry Research Institute